Homoeopathy in management of chronic ischaemic ulcer: An evidence-based case report

Malignant transformation of a chronic leg ulcer: a case report

Squamous cell carcinoma (SCC) is a malignant tumor of epidermal keratinocytes which may arise de novo, or at already affected skin areas of different etiology, including chronic vascular ulcers (CVUs). We present a 74-year-old female patient, hospitalized in the Department of Dermatology, with venous ulceration of the lower right leg, 10x5 cm in size, with well-demarcated edges, and the base co...

Melanoma associated with chronic leg ulcer: Case report

It has been stated that changes in skin coloration may accompany inflammatory reaction. In this context, the purpose of this case report is to present a patient of the Igbo ethnic group in SouthEastern Nigeria with reference to his developing malignant melanoma in a long standing leg ulcer. Hitherto, the association had been mainly that of squamous carcinoma. As for prevention, research in deve...

Tranexamic acid in the management of upper gastrointestinal bleeding: an evidence-based case report.

AIM to review the effectiveness of tranexamic acid therapy which has been proposed to reduce bleeding and in turn lower mortality rate. METHODS following literature searching based on our clinical question on Cochrane Library, PubMed, Clinical Key, EBSCO, Science Direct and Proquest, one systematic review that includes seven randomized controlled trials is obtained. The article meets validity...

Progress report. Aspirin in chronic gastric ulcer: an Australian experience.

Ketamine in chronic pain management: an evidence-based review.

Ketamine has diverse effects that may be of relevance to chronic pain including: N-methyl-D-aspartic acid, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, kainate, gamma-aminobutyric acid(A) receptors; inhibition of voltage gated Na(+) and K(+) channels and serotonin, dopamine re-uptake. Ketamine has been in clinical practice for over 30 yr; however, there has been little formal resea...